Ovarian cancer: Emerging molecular-targeted therapies

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Abstract

With about 22,000 new cases estimated in 2012 in the US and 15,500 related deaths, ovarian cancer is a heterogeneous and aggressive disease. Even though most of patients are sensitive to chemotherapy treatment following surgery, recurring disease is almost always lethal, and only about 30% of the women affected will be cured. Thanks to a better understanding of the molecular mechanisms underlying ovarian cancer malignancy, new therapeutic options with molecular-targeted agents have become available. This review discusses the rationale behind molecular-targeted therapies and examines how newly identified molecular targets may enhance personalized therapies for ovarian cancer patients. © 2012 Sourbier.

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APA

Sourbier, C. (2012). Ovarian cancer: Emerging molecular-targeted therapies. Biologics: Targets and Therapy. Dove Medical Press Ltd. https://doi.org/10.2147/btt.s24155

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