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The ER and cell calcium

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Calcium is one of the most versatile messengers in biological systems, translating developmental and environmental cues into cellular responses. The endoplasmic reticulum (ER) constitutes one of the most important calcium holding organelles in higher eukaryotes. Upon stimulation, calcium is released from the ER into the cytosol where it may trigger downstream effectors. However, the release of calcium may also affect internal ER functions, such as protein folding and secretion. It is therefore important not only to view cytosolic calcium signals as isolated events, but also in context to the organellar calcium status. In animals, the calcium levels of the ER can be sensed by other calcium resources, such as the plasma membrane, which may allow calcium uptake or release depending on the overall demand in the cell. In this chapter we have tried to convey the diverse aspects of calcium and its potential impact on different ER processes, and organellar communications, in plants. © Springer-Verlag Berlin Heidelberg 2006.




Persson, S., & Harper, J. (2006). The ER and cell calcium. Plant Cell Monographs.

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