Multidrug resistance-encoding plasmid from Aeromonas sp. strain P2G1

Abstract

A plasmid (pP2G1), which confers multidrug resistance in an environmental Aeromonas species, was completely sequenced using a shotgun approach. Plasmid pP2G1 encoded resistance to aminoglycosides and quinolones [aac(6′)-Ib-cr], β-lactams (blaOXA-1), chloramphenicol (catB3), macrolides [mphA-mrx-mphR], quaternary ammonium compounds (qacEΔ1), quinolones (qnrS2), rifampicin (arr-3) and sulphonamides (sul1). These findings suggest that Aeromonas species may potentially act as reservoirs of antibiotic resistance genes. © 2012 European Society of Clinical Microbiology and Infectious Diseases.