A case of BNT162b2 COVID ‐19 vaccine‐associated fulminant myocarditis in a very elderly woman

Abstract

Coronavirus disease 2019 (COVID‐19) vaccination is reportedly safe and effective. The histologic features of post‐COVID‐19 vaccination myocarditis are unknown. We present a case of a 77‐year‐old Japanese woman diagnosed with eosinophilic myocarditis using endomyocardial biopsy, 7 days after the second dose of BNT162b2 COVID‐19 vaccine. Steroid pulse therapy was effective.Myocarditis following COVID‐19 vaccination is a rare complication, and most cases are mild. However, the present case was a severe one in an elderly woman who responded remarkably to steroid pulse therapy. Eosinophilic myocarditis should be suspected in patients with heart failure after COVID‐19 vaccination.