C-Ag+-C based repetitive DNA sequence

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DNA is a convenient and well-studied tool for nanostructures fabrication. Metal-mediated hybridization of DNA strands opens up new possibilities for nanobiotechnology. In this work, we studied the possibility of long DNA formation from short ones by gluing them through the formation of C-Ag+-C complexes. Such long formations were investigated using static light scattering and atomic force microscopy. It was found that the duplexes can efficiently be linked in the presence of silver ions if the length of the cytosine sequence exceeds 6 nucleobases.




Popova, M. A., Rolich, V. I., Ramazanov, R. R., Kasyanenko, N. A., & Sokolov, P. A. (2020). C-Ag+-C based repetitive DNA sequence. In Journal of Physics: Conference Series (Vol. 1679). IOP Publishing Ltd. https://doi.org/10.1088/1742-6596/1679/2/022049

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