Complete resolution of urinary bladder condyloma acuminatum following definitive chemoradiotherapy for anal cancer

Abstract

OBJECTIVES To report the first occurrence of complete and sustained resolution of symptomatic condyloma acuminatum of the bladder with chemoradiotherapy. To describe the relevant patient details, imaging findings and chemoradiation treatment. PATIENT AND METHOD A 54-year-old female with extensive condyloma acuminatum of the bladder and a long history of human papilloma virus related anogenital disease was diagnosed with anal squamous cell carcinoma. Cystectomy for the bladder disease was delayed whilst chemoradiotherapy was administered for the anal cancer. RESULTS There was complete resolution of bladder disease at follow-up which has negated the need for cystectomy with its associated morbidity. Condyloma acuminatum has not recurred in 4 years of follow-up. CONCLUSION This is the first published report to our knowledge of the successful treatment of condyloma acuminatum of the bladder with chemoradiotherapy. The individual contributions of radiotherapy vs chemotherapy cannot be discerned. © 2011 BJU INTERNATIONAL.