N-alkylation of isatins utilizing KF/alumina

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Abstract

The N-alkylation of isatins by a variety of alkyl halides and one acrylate has been demonstrated utilizing KF/Al2O3 in acetonitrile (ACN) under microwave-irradiation (180 °C) or thermally at reflux. © ARKAT-USA, Inc.

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Clay, C. M., Abdallah, H. M., Jordan, C., Knisley, K., & Ketcha, D. M. (2012). N-alkylation of isatins utilizing KF/alumina. Arkivoc, 2012(6), 317–325. https://doi.org/10.3998/ark.5550190.0013.629

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