Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope

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Abstract

A high-throughput screening protocol for evaluating chimeric, self-sufficient P450 biocatalysts and their mutants against a panel of substrates was developed, leading to the identification of a number of novel biooxidation activities. © 2011 Robin et al.

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Robin, A., Köhler, V., Jones, A., Ali, A., Kelly, P. P., O’Reilly, E., … Flitsch, S. L. (2011). Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope. Beilstein Journal of Organic Chemistry, 7, 1494–1498. https://doi.org/10.3762/bjoc.7.173

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