Sequential transfer of information from one enzyme to the next within the confines of a protein kinase scaffold enhances signal transduction. Though frequently considered to be inert organizational elements, two recent reports implicate kinase-scaffolding proteins as active participants in signal relay. © 2013 Elsevier Ltd. All rights reserved.
Smith, F. D., & Scott, J. D. (2013, June 17). Scaffolding proteins: Not such innocent bystanders. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2013.05.002