Serum thyroid hormone levels in preeclampsia women in Gorgan

Abstract

Etiology of preeclampsia is clearly unknown. The aim of this study was to assess thyroid hormone levels in mild and severe preeclampsia women and compare them with healthy pregnant women. This study was done on 50 healthy pregnant and 50 preeclampsia women in the third trimester in the Sayyad Shirazi educational Hospital, Gynecology Department of Golestan University of Medical Sciences, Iran, 2014. There were significant differences in T4 level among mild preeclampsia and healthy pregnant women. There were also significant differences in T4 and T3 levels between severe, mild preeclampsia women and healthy pregnant women. We observed a significant positive correlation between systolic and diastolic blood pressure and thyroid hormones. Serum T3 and T4 levels were significantly increased with development of preeclampsia. There is association between thyroid hormone abnormalities and hypertension. The difference of our study with other findings could be related to different geographical areas, races and diets. Variation of thyroid functioning later in life may develop in preeclampsia women. Thus, it suggests that thyroid function test may necessary to screen preeclampsia women during pregnancy and after parturition.