Polycythemia Vera: A Malignancy in Hematology: Review Article

Abstract

ABSTRACT: Myeloid neoplasm is a condition in which myeloid cells can undergo excessive clonal proliferation. One classification of the disease is polycythemia vera.Polycythemia Vera (PV) is a condition where there is an increase in the number of red blood cells reaching 125% of the calculation based on body mass and sex. PV is caused by mutations in the JAK2 gene. PV disease diagnosisBased on the results of the history, physical examination and supporting examinations in the form of laboratory tests. PV disease can be managed with phlebotomy, administration of aspirin, and cytoreductive drugs. Patients with PV can survive more than 10 years if treated quickly and appropriately.