N,N-dimethylformamide (CAS No. 68-12-2)

Abstract

Ty/V-dimethylformamide (DMF) is a polar solvent termed the universal organic solvent because of its extensive miscibility with water and most common organic solvents. Often used in a variety of industrial processes, for example production of synthetic fibers, synthetic leather, polyurethane resin, surface coatings and obtaining pharmaceuticals products; DMF has high dipole moment (|i = 3,24 D) and high dielectric constant (e = 36,71 a 25°C). /V,/V-dimethylformamide is a common solvent for chemical reactions; on the other hand, can be utilized as precursor for various units ( -CHO, -CO, -NMe2, -CONMe2, - O, etc.) due to its structure. DMF has been employed as dehydrating agent, as a source for a reducing agents, as ligand in the preparation of metallic complexes and as catalyst. Indeed, DMF has played an important role in organic synthesis.