Vertical integration of NMR in the chemistry curriculum: A collaborative advanced laboratory experiment examining the structure-reactivity relationships in carbonyl reduction

Abstract

With the long-term goal of integrating NMR vertically across the ACS approved chemistry curriculum, we have developed a senior level collaborative experiment that examines the kinetics of the reduction of carbonyls and the structure-activity relationships in that reaction. Through data-sharing in a collaborative research-like experiment, students are able to form a complete picture of the factors that influence the rate of this common organic reaction, while honing their research and communication skills. © 2013 American Chemical Society.