Transition metals in organic synthesis, Part 98.1 Transition metal mediated total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin

Abstract

An efficient total synthesis of (±)-lavanduquinocin, a potent neuronal cell protecting alkaloid from Streptomyces viridochromogenes, is reported. Key-steps are an iron-mediated one-pot construction of the carbazole framework and a nickel-mediated coupling reaction. ©ARKAT-USA, Inc.