Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Its Subsequent Antiinflammatory Activity Evaluation

Abstract

Gold is the oldest dental restorative material, used for dental repairs for more than 4000 years and remains an important metal included in the dental sector. In a world where nanoparticle importance has been well established and preparation of nanoparticles has become much easier, it is important to assess if these nanoparticles can be extracted from plants as well. Along with its extraction, analysis of each property of the nanoparticle is essential. Pepper and eucalyptus remain two of the most important ingredients used in ayurveda and can be easily found in every household. The aim of this study was to extract gold nanoparticles using Eucalyptus and Piper longum and evaluate the antibacterial activity of the derived gold nanoparticles. Preparation of plant extract was done following which, extraction of gold nanoparticles was performed. Antiinflammatory properties of the gold nanoparticles were tested by albumin denaturation method and compared against the anti-inflammatory gold standard, Diclofenac sodium. The protein denaturation levels were measured, and the data was compiled. From this study, it can be concluded that gold nanoparticles derived from pepper and eucalyptus can be used as a potential source of anti-inflammatories.