Determining which neurite of a differentiating neuron is to become the axon is a crucial step in neuronal morphogenesis. Two groups (Barnes et al., 2007; Shelly et al., 2007) now report that axon specification in vivo is mediated by extracellular signals acting through the serine/threonine kinase LKB1. © 2007 Elsevier Inc. All rights reserved.
Winckler, B. (2007, May 4). BDNF Instructs the Kinase LKB1 To Grow an Axon. Cell. https://doi.org/10.1016/j.cell.2007.04.021