A Review on Recent Trends of 3D Printing Technology and Its Approaches in Current Drug Delivery

Abstract

Three-dimensional printing (3DP) is emerging as a groundbreaking technology in the pharmaceutical industry, promising transformative advancements in drug formulation and delivery. This innovative method enables the creation of personalized medications with precise dosages and tailored release profiles, addressing the limitations of traditional mass production. Despite its promising potential, the widespread adoption of 3DP in medicine faces several challenges. The primary issue is the lack of comprehensive regulatory guidelines, which creates uncertainty regarding standardization and quality control. Ensuring the quality and stability of 3D-printed drugs is another critical concern, with non-destructive evaluation methods like Near-Infrared and Raman spectroscopy being explored for real-time quality assessment. Additionally, current 3D printers often do not fully comply with Good Manufacturing Practice standards, which are essential for ensuring product consistency and safety. This study provides a comprehensive examination of recent trends and innovative approaches in 3DP technology applied to drug delivery systems, highlighting both the progress made and the challenges that need to be addressed. By examining current methodologies, materials, and applications, the research aims to elucidate the evolving landscape of 3D-printed pharmaceuticals. The study focuses on evaluating the feasibility, efficacy, and scalability of diverse 3DP approaches in developing personalized and precision drug formulations. These insights are intended to enhance the field of pharmaceutical sciences and support patient-centric healthcare by offering more customized and effective medication solutions. Through a comprehensive analysis of innovative 3DP techniques, the research seeks to contribute to the advancement of drug delivery systems, potentially revolutionizing the way medications are produced and administered.