A novel series of resveratrol modified by γ-Aminobutyric acid esters were designed and synthesized. Then, the products were characterized by 1H-NMR, 13C-NMR, and MS, and the melting point was determined. Molecular water solubility, polar surface area, and octanol-water partition were calculated, which correlated well with molecular transport through membranes and, therefore, enabled prediction of transport properties of drugs.
CITATION STYLE
Tian, B. R., Liu, J. Y., Ge, H. R., Wang, Z. Z., Huang, S. Y., Wang, Y. Y., … Zhang, R. X. (2019). The design, synthesis, and characterization of resveratrol derivatives modified by different γ-Aminobutyric acid esters. Journal of Chemistry, 2019. https://doi.org/10.1155/2019/3050486
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