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Azithromycin inhibits macrophage tumor necrosis factor secretion in response to both azithromycin-susceptible and azithromycin-resistant pneumococci

Journal of the Pediatric Infectious Diseases Society (2014) 3(2) 168-171
DOI: 10.1093/jpids/pit014
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Abstract

We studied the effect of azithromycin (AZM) on macrophage responses to pneumococci.We found that exposure of pneumococci to AZM led to reduced tumor necrosis factor (TNF) secretion by macrophages; this effect was observed in response to both AZM-susceptible and AZM-resistant (AZM-R) pneumococci.© The Author 2013. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved.

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Ingram, K., Marker, M., Meals, E., Talati, A. J., Spentzas, T., & Keith English, B. (2014). Azithromycin inhibits macrophage tumor necrosis factor secretion in response to both azithromycin-susceptible and azithromycin-resistant pneumococci. Journal of the Pediatric Infectious Diseases Society, 3(2), 168–171. https://doi.org/10.1093/jpids/pit014

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