Biochemistry of microbial itaconic acid production

Citations of this article
Mendeley users who have this article in their library.


This chapter presents the different transformation methods used for Trichoderma genetic transformation, including Agrobacterium tumefaciens [Rhizobium radiobacter]-mediated transformation, polyethylene glycol-mediated protoplast transformation, biolistic transformation, and electroporation. The advantages and disadvantages of these strategies are discussed. The use of genetic markers and reporter genes, gene targeting, site-specific recombination systems, and post-transcriptional gene silencing with RNA interference in the various stages of Trichoderma genetic engineering is discussed.




Steiger, M. G., Blumhoff, M. L., Mattanovich, D., & Sauer, M. (2013). Biochemistry of microbial itaconic acid production. Frontiers in Microbiology. Frontiers Research Foundation.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free