Role of Ghrelin, Leptin and Insulin Resistance in Development of Metabolic Syndrome in Obese Patients

Abstract

Objective: Obesity and its complications including metabolic syndrome (MetS) have been increased in children and adolescents recently. Leptin is known to play an important role in the pathogenesis of obesity. The objective of this study was to evaluate the relationship between Leptin, Ghrelin and Insulin resistance in the development of metabolic syndrome in obese persons.