Abstract
Serum samples from 30 HIV seronegative patients were treated with β propiolactone (BPL) to determine whether BPL interfaces with ELISA for specific antibodies against protein and carbohydrate antigens. BPL had no discernible effect on specific antibody measurements by ELISA. With the measuring need for specific antibody measurements in the management of HIV seropositive patients, it is reassuring that his laboratory safety measure does not impair the reliabiity of results.
Cite
CITATION STYLE
Agbarakwe, A. E., Misbah, S. A., Griffiths, H., & Chapel, H. M. (1993). Effect of β propiolactone on specific antibody measurements by ELISA. Journal of Clinical Pathology, 46(4), 368–369. https://doi.org/10.1136/jcp.46.4.368
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