Phase-dependent quantum optical coherence tomography

Abstract

Two-photon interference is a cornerstone of quantum optics, enabling imaging, sensing, and precision measurements that surpass classical limits. By harnessing the quantum interference of photon pairs, as demonstrated by the Hong-Ou-Mandel effect, this approach offers superior axial resolution and intrinsic dispersion cancellation, along with strong noise suppression arising from the precise temporal correlations between photons. Building on these principles, we present the theoretical framework and experimental realization of phase-dependent quantum optical coherence tomography (QOCT), a technique that employs phase-modulated two-photon interference for noninvasive morphological analysis of multilayered samples. We demonstrate that introducing controlled phase shifts to photon pairs in a Hong-Ou-Mandel interferometer effectively eliminates artifacts caused by reflections at different sample layers, thereby greatly improving the accuracy and reliability of QOCT measurements. This work advances the fundamental understanding and practical deployment of two-photon interference, overcoming a key limitation in applying QOCT to real-world applications such as biomedical imaging and materials characterization.