Videodensitometric quantitative angiography after coronary balloon angioplasty, compared to edge-detection quantitative angiography and intracoronary ultrasound imaging

Abstract

Aims: To assess the value of videodensitometric quantification of the coronary lumen after angioplasty by comparison to two Other techniques of coronary artery lumen quantification. Methods and Results: Videodensitometric quantitative angiography, edge detection quantitative angiography and 30 MHz intracoronary ultrasound imaging were performed after successful balloon angioplasty in 161 patients. Lumen cross-sectional areas were mean (SD) 2.82 (1.15) mm2 for edge detection quantitative angiography, 3.67 (1.5) mm2 for videodensitometric quantitative angiography and 5.32 (1.75) mm2 for intracoronary ultrasound imaging (P < 0.001). The correlation between intracoronary ultrasound imaging and videodensitometric quantitative angiography (r = 0.44) was almost similar to that of intracoronary ultrasound imaging and edge detection quantitative angiography (r = 0.47). The correlation between the three techniques was not significantly influenced by the presence of ruptures and dissections on intracoronary ultrasound imaging. The absence of calcifications improved the correlation between videodensitometry and intracoronary ultrasound imaging. Conclusions: The luminal dimensions as measured by videodensitometric quantitative angiography matched intracoronary ultrasound imaging derived dimensions more closely than edge detection quantitative angiography. Videodensitometric quantitative angiography represents an on-line alternative to intracoronary ultrasound imaging for quantitative analysis regardless of the degree of vessel damage. (C) 2000 The European Society of Cardiology.