Studies with enamines: Functionally substituted enamines as aldehyde equivalents in Gewald reactions

Abstract

Several aryl and functionally substituted enamines reacted with ethyl cyanoacetate and elemental sulfur to form 2-aminothiophene-3-carboxylic acid derivatives that proved to be excellent precursors for a variety of thiophenes. ©ARKAT-USA, Inc.