Therapeutic and toxicological effects of natural compounds: Data from HPV16-transgenic and ICR mice (Review)

Abstract

The aim of present mini-review was to highlight the effects of certain natural plant food compounds in animal models, analyzing their therapeutic effects and toxicological levels. Several natural compounds have been shown to promote health and to reduce the risk of disease due to their functional and nutraceutical properties. However, it has been observed that some diseases can still progress even in the presence of natural compounds. Thus, there is a need to conduct further research in order to elucidate the mechanisms underlying the functions and effects of natural compounds and to determine which products exert positive effects and which products have pharmacological potential to be applied in therapies.