In-vitro Anti-Inflammatory Evaluation of Crude Bombax ceiba Extracts

Abstract

Aims: Taking into account the previous findings on Bombax ceiba, the present work was decided to evaluate the anti-inflammatory activity of crude B. ceiba extracts by in-vitro experimental models, in order to characterize the role of this extract in affecting the inflammatory process. Study Design: Extraction of B. ceiba bark, phytochemical screening, and evaluation of in- vitro anti-inflammatory activity. Methodology: Petroleum ether, ethanol and aqueous extracts of B. ceiba barks were prepared by maceration technique and subjected to preliminary phytochemical tests. The in- vitro anti-inflammatory activity of all extracts (1000mcg/ml) was assessed by HRBC membrane stabilization method. Results: Ethanol extract showed significant (p<0.001) response followed by aqueous extract (p<0.01) when compared with standard, diclofenac potassium (50mcg/ml). Conclusion: The study concluded that the extracts possess and proves enough potential to be used as anti-inflammatory agents and directs the importance of further development.