Abstract
Chronic pain is often associated with hyperalgesia in cross-sectional studies. In the present study, a random cohort of 40-year-old individuals (n = 264) from the general population was assessed for low back pain (LBP) status and pressure pain threshold (PPT), with follow- up assessment 4 and 8 years later. Low PPT at baseline as a potential risk factor for the development of LBP was investigated longitudinally and the association between LBP and hyperalgesia was studied cross-sectionally at baseline and 8-year follow-up. Generalized (p <0.03) and localized pressure hyperalgesia (p<0.02) was found in participants with long-lasting LBP, but not with recent LBP (p<0.08). Of the participants without recent or long-lasting LBP, those with a low PPT at baseline (lower 10% percentile) had no increased risk of developing LBP (p<0.05). The findings indicate that PPT decreases as a consequence of long-lasting pain, whereas a low PPT seems not to constitute a separate risk factor for the development of LBP. © 2011 Springer-Verlag.
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O’Neill, S., Kjær, P., Graven-Nielsen, T., Manniche, C., & Arendt-Nielsen, L. (2011). Low pressure pain thresholds are associated with, but does not predispose for, low back pain. European Spine Journal, 20(12), 2120–2125. https://doi.org/10.1007/s00586-011-1796-4
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