The spectrum of serious infections among patients receiving immune checkpoint blockade for the treatment of melanoma

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Abstract

The risk of infection among patients receiving immune checkpoint blockade is unknown. We retrospectively reviewed medical records of 740 patients with melanoma who received immune checkpoint blockers. Serious infection occurred in 54 patients (7.3%). The main risk factors were receipt of corticosteroids and/or infliximab.

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Del Castillo, M., Romero, F. A., Argüello, E., Kyi, C., Postow, M. A., & Redelman-Sidi, G. (2016). The spectrum of serious infections among patients receiving immune checkpoint blockade for the treatment of melanoma. Clinical Infectious Diseases, 63(11), 1490–1493. https://doi.org/10.1093/cid/ciw539

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