ANTIGEN NON STRUKTURAL 1 (NS1) SEBAGAI MARKER SUSPEK INFEKSI DENGUE

Abstract

Dengue infection is considered as global health problem. The rate of the infection keeps on rising every year. The fatality rate due to dengue infection is categorized as high, especially the death caused by delayed healthcare. Laboratory checks up is very important to early diagnose the dengue suspect. Nonstructural protein 1 antigen (NS1) is considered to be sensitive as it specifically reacts to the existence of the dengue virus at the early stage of the infection (suspect). This research was aimed to find out the role of NS1 on suspected dengue patients. This research employed a descriptive approach or dengue suspected patients. The marker of dengue virus was obtained through medical records about the period of fever and the result of rumpel leed (RL) or tourniquet test from Roemani Hospital found the NS1 result from the laboratory checkup. The research finding showed that among 30 patients, 14 patients (46,6%) were the dengue suspects with 0-2 days fever, 3 RL positive (10%) and 5 NS1 positives (16,6%). 15 patients (50%) with 3-4 days of fever, 1 RL positive (3,3%) and 1 NS1 positive (3,3%). Also 1 patient with 5-7 days of fever and NS1 negative. Conclusions, not all dengue suspects in Roemani Hospital get positive NS1. 16.6% in fever symptoms 0-2 days, 3.3% in fever symptoms 2-4 days, and 0% in fever symptoms 5-7 days.