A New Rapid-Acting Antidepressant

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Abstract

The discovery of the strikingly rapid and robust antidepressant effects of r/s-ketamine for the treatment of antidepressant-resistant symptoms of depression has led to new insights into the biology of antidepressants and the FDA approval of its s-isomer, Esketamine (Spravato), the first mechanistically new treatment for depression in over 60 years. To view this Bench to Bedside, open or download the PDF.

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Krystal, J. H., Charney, D. S., & Duman, R. S. (2020, April 2). A New Rapid-Acting Antidepressant. Cell. Cell Press. https://doi.org/10.1016/j.cell.2020.02.033

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