Clarithromycin and new derivatives of erythromycin

  • Adachi T
  • Morimoto S
N/ACitations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Since erythromycin’ s the discovery in 1952 [1], it has been one of the most useful macrolide antibiotics, having the highest antibacterial activity and low toxicity. In order to achieve high antibacterial activities against a wide variety of pathogens and favorable pharmacokinetic properties, tremendous efforts have been made related to chemical modification [2, 3]. In the 1970s and 1980s, dirithromycin, flurithromycin, and davercin were synthesized and evaluated. Erythromycin itself is quite unstable under acidic conditions, so esters, salts, and various formulations also have been developed.

Cite

CITATION STYLE

APA

Adachi, T., & Morimoto, S. (2002). Clarithromycin and new derivatives of erythromycin. In Macrolide Antibiotics (pp. 53–72). Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-8105-0_5

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free