Abstract
The peculiarities of helix-coil transition of DNA at complex-formation with cis-diamminedichlorplatinum (II) (cis-DDP) have been investigated in acidic environment by UV absorbance technique. It is shown that observed features of behavior AT (pH) and Tm (pH) DNA at pH 2.8-3.0 are possible to explain by formation in DNA of pseudo-ring structures at covalent linking of cis-DDP with DNA.
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Dalyan, Y. B., Haroutiunian, T. S., Haroutiunian, S. G., & Vardevanyan, P. O. (2003). Melting of complexes of DNA-cis-DDP in acidic environment. Experimental and Molecular Medicine, 35(6), 534–537. https://doi.org/10.1038/emm.2003.69
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