Multi-component one-pot reactions for the synthesis of spirooxindole-pyrano[2,3-c]pyrazole derivatives

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Abstract

A highly efficient strategy for the one-pot synthesis of multi-substituted spirooxindol-pyrano[2,3-c]pyrazole derivatives was developed. The product formed in good yield from the reaction of acetylenedicarboxylate, hydrazine, isatin, and (E)-1-methylthio-1-methylamino-2-nitroethylene in the presence of Et3N catalyst. This simple and convenient method could also be used to prepare similar types of product.

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Feng, J., Ablajan, K., Ma, X., Li, W., & Obul, M. (2016, January 1). Multi-component one-pot reactions for the synthesis of spirooxindole-pyrano[2,3-c]pyrazole derivatives. Chinese Journal of Organic Chemistry. Science Press. https://doi.org/10.6023/cjoc201507011

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