Bipolar disorder against a background of a rare vascular dementia

Abstract

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare cause of vascular dementia which is underdiagnosed and whose prevalence is currently undetermined. Here, Drs Bangash and Saad describe a highly uncommon case of manic symptoms in CADASIL and the diagnostic criteria and clinical management for this condition.