Synthesis of α, α′-bis(substituted benzylidene)ketones catalysed by a SOCl2/EtOH reagent

Abstract

The cross-aldol condensations of cyclopentanone, cyclohexanone and acetone with benzaldehyde or cinnamaldehyde were catalysed in the presence of SOCl 2, in anhydrous ethanol to synthesise α, α′ -bis(substituted benzylidene) ketones with excellent yields(92-97%).