CA15.3 serum concentrations in older women with infiltrating ductal carcinomas of the breast

0Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.

Abstract

© 2014 by the authors; licensee MDPI, Basel, Switzerland. Breast cancer is currently becoming a disease of the elderly. We have studied the relation between CA 15.3 serum concentrations and clinical-pathological parameters in 69 women with IDC aged over 70 years (76.3 ± 4.2; range: 71-88; median 76). A group of 205 women with the same tumor but aged <70 years (62.8 ± 4.0; range: 55-70; median 63) was also considered for comparison. Tumor size, axillary lymph node involvement, distant metastasis and histological grade were taken account. Serum CA 15.3 was determined by luminescence assay. CA 15.3 serum concentrations ranged between 6 and 85 U/mL (median 22.9 U/mL), and were higher only in patients with greater (qualitative and quantitative; p: 0.041) tumor size. Our results show that in women with IDCs, and aged over 70 years, serum CA 15.3 serum concentrations are associated exclusively with a  greater tumor size, being these findings different to those described in women with the same subtype of tumor considered as a whole or with lower age.

Cite

CITATION STYLE

APA

Ruibal, Á., Aguiar, P., Del Río, M. C., Padín-Iruegas, M. E., Arias, J. I., & Herranz, M. (2014). CA15.3 serum concentrations in older women with infiltrating ductal carcinomas of the breast. International Journal of Molecular Sciences, 15(11), 19870–19876. https://doi.org/10.3390/ijms151119870

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free