In-vitroanti-urolithiatic activity of theriophonum minutum and remusatia vivipara

Abstract

Kidney stone is a very common disease worldwide threat. The calcium oxalate is the important compound of calculi formation in the urinary tract. Traditional studies on use of herbal based medicinal plants for treating severe disease is satisfying its bad to advanced world. In this regard, the study was analyzed with an objective to carry out the role of Theriophonum minutum and Remusatia vivipara leaves extract in different solvents to reduce stone formation and to find out the concentration of medicinal plant extract exhibit dissolution rate of kidney stones In dissolution studies, the extract of Remusatia vivipara has greater ability to dissolve artificial calcium stones and kidney stones rather than the standard drug. Calcium oxalate crystal formation was stimulated by the sodium oxalate solutions. The effect of different extract concentration was applied to measure the dissolution rate, turbidity, nucleation aggregation assay. The extract of Theriophonum minutum and Remusatia vivipara reflected the blocking action in both of nucleation and aggregation to better level.