Do cardiac aneurysms blow out?

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The possibility is suggested that cardiac aneurysms are formed when an infarcted region of the ventricular wall becomes elastically unstable and "blows out". The consequence of such a blowout could be a large saccular aneurysm or even cardiac rupture. We use a nonlinear stress-strain relation capable of describing both the passive and active myocardial wall to examine this possibility in terms of large-deformation membrane theory. Ventricular infarcts made of a material having physical properties like rubber would be expected to blow out, but those made of passive myocardium would not. © 1979, The Biophysical Society. All rights reserved.




Bogen, D. K., & McMahon, T. A. (1979). Do cardiac aneurysms blow out? Biophysical Journal, 27(2), 301–316.

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