Cardiac Transplantation Following Storage of the Donor Heart by a Portable Hypothermic Perfusion System

83Citations
Citations of this article
12Readers
Mendeley users who have this article in their library.

Abstract

Four patients have undergone heterotopic heart transplantation with donor hearts stored by a portable hypothermic perfusion system. Total ischemic periods ranged from 6 hours 55 minutes to 16 hours 50 minutes. One heart, transplanted into a patient who had acutely rejected a previous graft, suffered accelerated, irreversible, acute rejection within five days, associated with strong antibody formation; donor heart function was never good. In the 3 remaining patients, donor heart function was good after initially being poor for a few hours in 2 patients. One patient died of long-term rejection after 6 months and 1 of tuberculous meningitis after 10 months; 1 remains alive at 15 months. Neither preservation of the donor heart for periods in excess of approximately 4 hours nor the use of continuous hypothermic perfusion as a method of preservation appears to have been reported previously in the context of the clinical situation. © 1984, The Society of Thoracic Surgeons. All rights reserved.

Cite

CITATION STYLE

APA

Wicomb, W. N., Cooper, D. K. C., Novitzky, D., & Barnard, C. N. (1984). Cardiac Transplantation Following Storage of the Donor Heart by a Portable Hypothermic Perfusion System. Annals of Thoracic Surgery, 37(3), 243–248. https://doi.org/10.1016/S0003-4975(10)60333-5

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free