Psoriatic arthritis is a chronic inflammatory condition in which unbalanced inflammatory pathways act as key drivers of a wide range of articular and extraarticular manifestations. It is associated with a high prevalence of cardiovascular (CV) disease and risk factors. The precise pathogenetic mechanism of CV involvement has still to be clarified, but certain inflammatory cytokines play a key role in the atherosclerotic process. Studies have shown the potentially beneficial role of disease-modifying antirheumatic drug–induced immunosuppression and also anti–tumor necrosis factor drugs on CV diseases.
Atzeni, F., Caso, F., Masala, I. F., & Sarzi-Puttini, P. (2017). Cardiovascular Involvement in Psoriatic Arthritis. In Handbook of Systemic Autoimmune Diseases (Vol. 14, pp. 409–426). Elsevier Ltd. https://doi.org/10.1016/B978-0-12-803997-7.00016-8