Castleman's disease of the neck

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Abstract

Castleman's disease is an uncommon benign disease of unknown etiology that induces reactive lymph node hyperplasia. There are 2 histologic subtypes of Castleman's disease: hyaline vascular type and plasma cell type. Tissue biopsy is necessary for a definitive diagnosis. Castleman's disease of the neck occurs rarely. On reviewing the literature, most Castleman's disease of the neck presented with a single mass. We report here an 80-year-old man with 2 neck masses of 1 year's duration. A 4-cm firm movable mass in the left submandibular area and another 2-cm firm movable mass in the left level IV area were noted. The patient was diagnosed with Castleman's disease of the neck after resection of I of the masses. There was no evidence of progression or recurrence of the disease after 21 months of follow-up. We suggest that this was a rare case of multicentric cervical Castleman's disease. © 2007 Elsevier. All rights reserved.

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Chen, C. C., Jiang, R. S., Chou, G., & Wang, C. P. (2007). Castleman’s disease of the neck. Journal of the Chinese Medical Association, 70(12), 556–558. https://doi.org/10.1016/S1726-4901(08)70060-1

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