In this chapter, students will be introduced to the challenges of organ transplantation and the ensuing need to find alternative ways to replace failing organs and tissues. The main organ systems are then briefly summarized, followed by examples of how much their cells and vascularization routes can be different. This helps to emphasize to the students the need to know the anatomy of the animal to be dissected and the vascular structure of the chosen organ. Having adequate vascular access to the organ is required for both live cells isolation and organ decellularization -- procedures that students will be performing during this course. The sources of animal tissue, instruments used for dissection and organ removal, and use of heparin and collagenase are then briefly discussed. The chapter is concluded by asserting the importance of anesthesia and the ethical treatment of animals.
Grigoryan, M., & Sarvazyan, N. (2020). Organ Structure and Vascularization (pp. 15–27). https://doi.org/10.1007/978-3-030-39698-5_2