Vertebral arteriovenous fistulae (AVF) in neurofibromatosis Type 1: A report of two cases

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Abstract

Spontaneous vertebral arteriovenous fistulae (AVF) associated with neurofibromatosis Type 1 (NF-1) is a rare occurrence in the previous reports. We presented two female NF-1 patients with a diagnosis of cervical vertebral AVF treated with endovascular approach. The fistula in the first case was successfully obliterated by feeder occlusion; whereas, for the second one, new fistulae were formed following the primary fistula closure. Anatomic and hemodynamic changes in combination with dysplastic vascular condition in NF-1 may contribute to fistulae formation de novo. The present case points out a rare challenge encountered in the treatment of vertebral arteriovenous fistula complicated by previous fistula obliteration in NF-1.

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Gao, P., Chen, Y., Zhang, H., Zhang, P., & Ling, F. (2013). Vertebral arteriovenous fistulae (AVF) in neurofibromatosis Type 1: A report of two cases. Turkish Neurosurgery, 23(2), 289–293. https://doi.org/10.5137/1019-5149.JTN.4993-11.0

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