Current treatment and future directions in the management of chronic hepatitis B viral infection

Abstract

Chronic HBV infection continues to pose a very serious health care problem worldwide. Exciting new treatments for the management of HBV continue to push viral levels to lower thresholds; improvements in histology, even in the short-term, are remarkable; and the safety of emerging agents remains very favorable. There are also emerging molecular tools and possibly treatments to further advance the therapeutic options for chronic HBV disease. © 2005 Elsevier Inc. All rights reserved.