Development of template-directed reversible DNA photocrosslinking

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Abstract

We describe a novel reversible DNA interstrand photocrosslinking reaction via the artificial nucleoside (X). Oligodeoxynucleotide (ODN) containing X can be photocrosslinked by irradiation at 366 nm for 1 s, and the photocrosslinked ODN can be split by irradiation at 312 nm for 60 s.

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Yoshimura, Y., Ozaki, G., & Fujimoto, K. (2008). Development of template-directed reversible DNA photocrosslinking. Nucleic Acids Symposium Series (2004), (52), 423–424. https://doi.org/10.1093/nass/nrn215

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