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DNA sequencing for confirmation of rifampin resistance detected by cepheid xpert MTB/RIF assay

Journal of Clinical Microbiology (2015) 53(5) 1752-1753
DOI: 10.1128/JCM.03433-14
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Abstract

DNA sequencing of rpoB and culture-based drug susceptibility results were evaluated for samples referred for confirmation of rifampin resistance detected by the Cepheid Xpert MTB/RIF assay. Silent mutations and mutations associated with low-level resistance were found in the study population. These data support CDC recommendations to confirm Xpert rifampin resistance results.

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McAlister, A. J., Driscoll, J., & Metchock, B. (2015). DNA sequencing for confirmation of rifampin resistance detected by cepheid xpert MTB/RIF assay. Journal of Clinical Microbiology, 53(5), 1752–1753. https://doi.org/10.1128/JCM.03433-14

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