Chemical constituents from roots of gymnotheca chinensis

Abstract

Chromatographic separation and spectral analysis were performed to separate and identify the chemical components of the roots of Gymnotheca chinensis, respectively. Four compounds were isolated and identified as 5-decanoyl-2-nonyl pyridine (1), stigmastan-3,6-dione (2), stigmast-4-en-3,6-dione (3) and daucosterol (4). Compounds 1∼3 were obtained from this genus for the first time. Compounds 1-3 showed cytotoxic activity on human hepatoma (SMMC-7721 and Hep3B) cell lines.