ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data.

122Citations
Citations of this article
92Readers
Mendeley users who have this article in their library.

Abstract

ChIPOTle (Chromatin ImmunoPrecipitation On Tiled arrays) takes advantage of two unique properties of ChIP-chip data: the single-tailed nature of the data, caused by specific enrichment but not specific depletion of genomic fragments; and the predictable enrichment of DNA fragments adjacent to sites of direct protein-DNA interaction. Implemented as a Microsoft Excel macro written in Visual Basic, ChIPOTle uses a sliding window approach that yields improvements in the identification of bona fide sites of protein-DNA interaction.

Cite

CITATION STYLE

APA

Buck, M. J., Nobel, A. B., & Lieb, J. D. (2005). ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data. Genome Biology, 6(11). https://doi.org/10.1186/gb-2005-6-11-r97

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free