Chlorpyrifos exposure and respiratory health among adolescent agricultural workers

10Citations
Citations of this article
24Readers
Mendeley users who have this article in their library.

Abstract

© 2014 by the authors; licensee MDPI, Basel, Switzerland. Chlorpyrifos (CPF) is a commonly used organophosphate insecticide (OP). In adults, exposure to OPs has been inconsistently associated with reduced lung function. OP exposure and lung function has not been assessed in adolescents. The objective of this study was to assess CPF exposure and lung function among Egyptian adolescents. We conducted a 10-month study of male adolescent pesticide applicators (n = 38) and non-applicators of similar age (n = 24). Urinary 3,5,6-trichloro-2-pyridinol (TPCy), a CPF-specific metabolite, was analyzed in specimens collected throughout the study. Spirometry was performed twice after pesticide application: day 146, when TCPy levels were elevated and day 269,when TCPy levels were near baseline. Applicators had higher levels of TCPy (mean cumulative TCPy day 146 = 33,217.6; standard deviation (SD) = 49,179.3) than non-applicators (mean cumulative TCPy day 146 = 3290.8; SD = 3994.9). Compared with non-applicators, applicators had higher odds of reporting wheeze, odds ratio = 3.41(95% CI: 0.70; 17.41). Cumulative urinary TCPy was inversely associated with spirometric measurements at day 146, but not at day 269. Although generally non-significant, results were consistent with an inverse association between exposure to CPF and lung function.

Author supplied keywords

Cite

CITATION STYLE

APA

Catherine L, C., Manal Al, B., Ahmed, A. I., Gaafar Abdel, R., Olfat, H., James R, O., … Matthew R, B. (2014). Chlorpyrifos exposure and respiratory health among adolescent agricultural workers. International Journal of Environmental Research and Public Health, 11(12), 13117–13129. https://doi.org/10.3390/ijerph111213117

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free